Overproduction of uric acid, generated from the metabolism of purines, has been proven to play emerging roles in human disease.
Table of contents
- How is Uric Acid produced?
- What are the effects of elevated uric acid levels?
- What foods can I include?
- High-purine food: Avoid
- What other guidelines should I follow?
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How is Uric Acid produced?
Purines are a natural substance found in some foods. These are molecules made up of carbon and nitrogen atoms and are found in the cells’ DNA and RNA.
Purines aren’t all bad, but you should avoid high amounts.
In humans the final compound of purines catabolism is uric acid. When your body digests purinw, it produces a waste product called uric acid.
All other mammals possess the enzyme uricase that converts uric acid to allantoin which is easily eliminated through urine.
Most of the time, a high uric acid level occurs when your kidneys don’t eliminate uric acid efficiently, thus potentially leading to a number of health issues.
What are the effects of elevated uric acid levels?
Elevated uric acid levels, known as Hyperuricemia may cause
- Worsening of kidney function
- Damage to affected joints
- A flare-up of a painful type of arthritis called Gout.
Gout is a painful medical condition characterised by urate crystal deposition in various joints
Lifestyle measures, such as dietary changes can help lower levels of uric acid that deposits in joints and causes gout.
However, for most people, changes in diet alone are not enough to prevent gout. To reduce uric acid levels enough to stop attacks, medication is usually needed. Still making changes in what you eat can lead to fewer gouty flares.
What foods can I include?
Low-purine foods: Eat sufficiently
|Include foods that are low in purine|
|Eggs, nuts, and peanut butter|
|Low-fat and fat-free cheese and ice-cream|
|Skimmed or 1%milk, cottage cheese, dairy products|
|Soup made without meat extract or broth|
|All fruit and fruit juices|
|Bread, pasta, rice, cake, cornbread, popcorn, oats|
|Water, soda, tea, coffee and cocoa|
|Sugar, sweets and gelatin|
|Fat and oil-sunflower seed oil, olive oil|
Medium-purine foods: Eat moderately
High-purine food: Avoid
What can one eat: eggs, fruits and vegetables, rice and wheat etc.
What other guidelines should I follow?
Increase liquid intake
Liquid can help your body get rid of extra uric acid. Drink 8 to 16(eight ounces) cups of liquid each day. At least half of the liquid should be water.
Limit or avoid alcohol
Alcohol (especially beer) increases the risk of a gout attack. Beer contains a high amount of purine.
Maintain a healthy weight
If one is overweight, one should lose weight slowly. Weight loss can help decrease the amount of stress on joints. Regular exercise can help lose weight if one is overweight, or maintain your weight, if of normal weight.